O-GlcNAcylation regulates neurofilament-light assembly and function and is perturbed by Charcot-Marie-Tooth disease mutations

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The neurofilament (NF) cytoskeleton is critical for neuronal morphology and function. In particular, the neurofilament-light (NF-L) subunit is required for NF assembly in vivo and is mutated in subtypes of Charcot-Marie-Tooth (CMT) disease. NFs are highly dynamic, and the regulation of NF assembly s...

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Detalles Bibliográficos
Autores principales: Huynh, Duc T., Tsolova, Kalina N., Watson, Abigail J., Khal, Sai Kwan, Green, Jordan R., Li, Di, Hu, Jimin, Soderblom, Erik J., Chi, Jen-Tsan, Evans, Chantell S., Boyce, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582078/
https://www.ncbi.nlm.nih.gov/pubmed/37848414
http://dx.doi.org/10.1038/s41467-023-42227-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582078/
https://www.ncbi.nlm.nih.gov/pubmed/37848414
http://dx.doi.org/10.1038/s41467-023-42227-0

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