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ALKBH5 controls the meiosis-coupled mRNA clearance in oocytes by removing the N (6)-methyladenosine methylation
N(6)-methyladenosine (m(6)A) maintains maternal RNA stability in oocytes. One regulator of m(6)A, ALKBH5, reverses m(6)A deposition and is essential in RNA metabolism. However, the specific role of ALKBH5 in oocyte maturation remains elusive. Here, we show that Alkbh5 depletion causes a wide range o...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582257/ https://www.ncbi.nlm.nih.gov/pubmed/37848452 http://dx.doi.org/10.1038/s41467-023-42302-6 |