ALKBH5 controls the meiosis-coupled mRNA clearance in oocytes by removing the N (6)-methyladenosine methylation

N(6)-methyladenosine (m(6)A) maintains maternal RNA stability in oocytes. One regulator of m(6)A, ALKBH5, reverses m(6)A deposition and is essential in RNA metabolism. However, the specific role of ALKBH5 in oocyte maturation remains elusive. Here, we show that Alkbh5 depletion causes a wide range o...

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Detalles Bibliográficos
Autores principales: Bai, Long, Xiang, Yu, Tang, Minyue, Liu, Shuangying, Chen, Qingqing, Chen, Qichao, Zhang, Min, Wan, Shan, Sang, Yimiao, Li, Qingfang, Wang, Sisi, Li, Zhekun, Song, Yang, Hu, Xiaoling, Mao, Luna, Feng, Guofang, Cui, Long, Ye, Yinghui, Zhu, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582257/
https://www.ncbi.nlm.nih.gov/pubmed/37848452
http://dx.doi.org/10.1038/s41467-023-42302-6

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