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Enantioselective S(N)2 Alkylation of Homoenolates by N‐Heterocyclic Carbene Catalysis (Adv. Sci. 29/2023)

Enantioselective β‐Alkylation In article number 2303517, Yong Huang, Jiean Chen, and co‐workers, describe a novel S(N)2 reaction mode for NHC‐mediated homoenolate chemistry, enabling enantioselective β‐alkylation, allylation and propargylation of enals. By combining with a “transient acyl trap” stra...

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Detalles Bibliográficos
Autores principales: Li, En, Tang, Kai, Ren, Zhuhui, Liao, Xiaoyun, Liu, Qianchen, Huang, Yong, Chen, Jiean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582437/
http://dx.doi.org/10.1002/advs.202370196