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Loss of ZBED6 Protects Against Sepsis‐Induced Muscle Atrophy by Upregulating DOCK3‐Mediated RAC1/PI3K/AKT Signaling Pathway in Pigs

Sepsis‐induced muscle atrophy often increases morbidity and mortality in intensive care unit (ICU) patients, yet neither therapeutic target nor optimal animal model is available for this disease. Here, by modifying the surgical strategy of cecal ligation and puncture (CLP), a novel sepsis pig model...

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Detalles Bibliográficos
Autores principales: Liu, Huan, Pan, Dengke, Li, Pu, Wang, Dandan, Xia, Bo, Zhang, Ruixin, Lu, Junfeng, Xing, Xiangyang, Du, Jiaxiang, Zhang, Xiao, Jin, Long, Jiang, Lin, Yao, Linong, Li, Mingzhou, Wu, Jiangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582467/
https://www.ncbi.nlm.nih.gov/pubmed/37551034
http://dx.doi.org/10.1002/advs.202302298