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In vitro vascularized immunocompetent patient-derived model to test cancer therapies

This work describes a patient-derived tumoroid model (PDTs) to support precision medicine in lung oncology. The use of human adipose tissue-derived microvasculature and patient-derived peripheral blood mononuclear cells (PBMCs) permits to achieve a physiologically relevant tumor microenvironment. Th...

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Detalles Bibliográficos
Autores principales: Lê, Hélène, Deforges, Jules, Hua, Guoqiang, Idoux-Gillet, Ysia, Ponté, Charlotte, Lindner, Véronique, Olland, Anne, Falcoz, Pierre-Emanuel, Zaupa, Cécile, Jain, Shreyansh, Quéméneur, Eric, Benkirane-Jessel, Nadia, Balloul, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582498/
https://www.ncbi.nlm.nih.gov/pubmed/37860774
http://dx.doi.org/10.1016/j.isci.2023.108094