Cargando…

In vitro vascularized immunocompetent patient-derived model to test cancer therapies

This work describes a patient-derived tumoroid model (PDTs) to support precision medicine in lung oncology. The use of human adipose tissue-derived microvasculature and patient-derived peripheral blood mononuclear cells (PBMCs) permits to achieve a physiologically relevant tumor microenvironment. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lê, Hélène, Deforges, Jules, Hua, Guoqiang, Idoux-Gillet, Ysia, Ponté, Charlotte, Lindner, Véronique, Olland, Anne, Falcoz, Pierre-Emanuel, Zaupa, Cécile, Jain, Shreyansh, Quéméneur, Eric, Benkirane-Jessel, Nadia, Balloul, Jean-Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582498/ https://www.ncbi.nlm.nih.gov/pubmed/37860774 http://dx.doi.org/10.1016/j.isci.2023.108094

Ejemplares similares

Vascularization of Patient-Derived Tumoroid from Non-Small-Cell Lung Cancer and Its Microenvironment
por: Seitlinger, Joseph, et al.
Publicado: (2022)

Patient-Derived Tumoroid for the Prediction of Radiotherapy and Chemotherapy Responses in Non-Small-Cell Lung Cancer
por: Nounsi, Anasse, et al.
Publicado: (2023)

Patient-Derived Lung Tumoroids—An Emerging Technology in Drug Development and Precision Medicine
por: Lê, Hélène, et al.
Publicado: (2022)

Nanoengineered implant as a new platform for regenerative nanomedicine using 3D well-organized human cell spheroids
por: Keller, Laetitia, et al.
Publicado: (2017)

Potential Implantable Nanofibrous Biomaterials Combined with Stem Cells for Subchondral Bone Regeneration
por: Smaida, Rana, et al.
Publicado: (2020)

Quercetin potentializes the respective cytotoxic activity of gemcitabine or doxorubicin on 3D culture of AsPC-1 or HepG2 cells, through the inhibition of HIF-1α and MDR1
por: Hassan, Sarah, et al.
Publicado: (2020)

Maxillary Bone Regeneration Based on Nanoreservoirs Functionalized ε-Polycaprolactone Biomembranes in a Mouse Model of Jaw Bone Lesion
por: Strub, Marion, et al.
Publicado: (2018)

Bone substitutes: a review of their characteristics, clinical use, and perspectives for large bone defects management
por: Fernandez de Grado, Gabriel, et al.
Publicado: (2018)

Temporomandibular Joint Regenerative Medicine
por: Van Bellinghen, Xavier, et al.
Publicado: (2018)

Preclinical safety study of a combined therapeutic bone wound dressing for osteoarticular regeneration
por: Keller, Laetitia, et al.
Publicado: (2019)

Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes
por: Harmouch, Ezeddine, et al.
Publicado: (2020)

Donors in lung transplantation: does age matter?
por: Ponte, Charlotte, et al.
Publicado: (2023)

Mechanistic Illustration: How Newly-Formed Blood Vessels Stopped by the Mineral Blocks of Bone Substitutes Can Be Avoided by Using Innovative Combined Therapeutics
por: Bornert, Fabien, et al.
Publicado: (2021)

World’s First Long-Term Colorectal Cancer Model by 3D Bioprinting as a Mechanism for Screening Oncolytic Viruses
por: McGuckin, Colin, et al.
Publicado: (2023)

Slug Controls Stem/Progenitor Cell Growth Dynamics during Mammary Gland Morphogenesis
por: Nassour, Mayssa, et al.
Publicado: (2012)

Implication of Toll/IL-1 receptor domain containing adapters in Porphyromonas gingivalis-induced inflammation
por: Bugueno, Isaac M, et al.
Publicado: (2021)

Extracorporeal life support use in limited lung function: a narrative review
por: Santos Silva, João, et al.
Publicado: (2023)

Reply: Comment on ‘KRAS and BRAF mutations are prognostic biomarkers in patients undergoing lung metastasectomy of colo-rectal cancer'
por: Renaud, Stéphane, et al.
Publicado: (2015)

Principi e indicazioni dell’assistenza circolatoria e respiratoria extracorporea in chirurgia toracica
por: Reeb, J., et al.
Publicado: (2016)

Principi e indicazioni dell’assistenza circolatoria e respiratoria extracorporea in chirurgia toracica()
por: Reeb, J., et al.
Publicado: (2017)

Cell Type Influences Local Delivery of Biomolecules from a Bioinspired Apatite Drug Delivery System
por: Alhamdi, Jumana, et al.
Publicado: (2018)

Updates on Anticancer Therapy-Mediated Vascular Toxicity and New Horizons in Therapeutic Strategies
por: Hsu, Po-Yen, et al.
Publicado: (2021)

Nano-Structured Ridged Micro-Filaments (≥100 µm Diameter) Produced Using a Single Step Strategy for Improved Bone Cell Adhesion and Proliferation in Textile Scaffolds
por: Behary, Nemeshwaree, et al.
Publicado: (2022)

Application of Chitosan in Bone and Dental Engineering
por: Aguilar, Alicia, et al.
Publicado: (2019)

Contribution of Statins towards Periodontal Treatment: A Review
por: Petit, Catherine, et al.
Publicado: (2019)

KRAS and BRAF mutations are prognostic biomarkers in patients undergoing lung metastasectomy of colorectal cancer
por: Renaud, S, et al.
Publicado: (2015)

Porphyromonas gingivalis bypasses epithelial barrier and modulates fibroblastic inflammatory response in an in vitro 3D spheroid model
por: Bugueno, Isaac Maximiliano, et al.
Publicado: (2018)

Flavaglines as natural products targeting eIF4A and prohibitins: From traditional Chinese medicine to antiviral activity against coronaviruses
por: Nebigil, Canan G., et al.
Publicado: (2020)

40S recruitment in the absence of eIF4G/4A by EMCV IRES refines the model for translation initiation on the archetype of Type II IRESs
por: Chamond, Nathalie, et al.
Publicado: (2014)

Polymer-Based Instructive Scaffolds for Endodontic Regeneration
por: Zein, Naimah, et al.
Publicado: (2019)

Modulation of immune-inflammatory responses through surface modifications of biomaterials to promote bone healing and regeneration
por: Batool, Fareeha, et al.
Publicado: (2021)

Outcome of lung oligometastatic patients treated with stereotactic body irradiation
por: Virbel, Guillaume, et al.
Publicado: (2022)

Rescue of non-sense mutated p53 tumor suppressor gene by aminoglycosides
por: Floquet, Célia, et al.
Publicado: (2011)

Porphyromonas gingivalis and its lipopolysaccharide differently modulate epidermal growth factor–dependent signaling in human gingival epithelial cells
por: Elkaim, R., et al.
Publicado: (2017)

Bone Grafts, Bone Substitutes and Regenerative Medicine Acceptance for the Management of Bone Defects Among French Population: Issues about Ethics, Religion or Fear?
por: Offner, Damien, et al.
Publicado: (2019)

A therapeutic oxygen carrier isolated from Arenicola marina decreased P. gingivalis induced inflammation and tissue destruction
por: Batool, Fareeha, et al.
Publicado: (2020)

Comparative effectiveness of nonsurgical interventions in the treatment of patients with knee osteoarthritis: A PRISMA-compliant systematic review and network meta-analysis
por: Naja, Moustafa, et al.
Publicado: (2021)

Eruption of Bioengineered Teeth: A New Approach Based on a Polycaprolactone Biomembrane
por: Stutz, Céline, et al.
Publicado: (2021)

Extracorporeal Membrane Oxygenation for Critically Ill Patients with COVID-19–related Acute Respiratory Distress Syndrome: Worth the Effort?
por: Falcoz, Pierre-Emmanuel, et al.
Publicado: (2020)

Prediction of regulatory long intergenic non-coding RNAs acting in trans through base-pairing interactions
por: Deforges, Jules, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ogkifbmmfsqk1f93jm0ejjkq43