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Macrophage colony-stimulating factor ameliorates myocardial injury in mice after myocardial infarction by regulating cardiac macrophages through the P2X7R/NLRP3/IL-1β signal pathway

AIMS: To investigate the effects of M-CSF on myocardial injury in mice after MI by regulating different types of cardiac macrophages through the P2X7R/NLRP3/IL-1β signal pathway. METHODS: A total of 60 C57BL/6J WT mice were used, with the Sham Group subjected to ligation without ligation through the...

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Detalles Bibliográficos
Autores principales: Zhang, Shu-Juan, Huang, Cong-Xin, Zhao, Qing-Yan, Huang, He, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582506/
https://www.ncbi.nlm.nih.gov/pubmed/37860548
http://dx.doi.org/10.1016/j.heliyon.2023.e20805