Peripheral CCL2 induces inflammatory pain via regulation of I(h) currents in small diameter DRG neurons

The C-C motif chemokine ligand 2 (CCL2) has been implicated in chronic pain, but its exact mechanism of peripheral sensitization is unknown. In this study, we aimed to clarify the mechanism of CCL2 regulation of ion channels. Our behavioral experiments revealed that ZD7288, a blocker of I(h) current...

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Detalles Bibliográficos
Autores principales: Li, Lamei, Liu, Yuanying, Hu, Wenchao, Yang, Jing, Ma, Suibin, Tian, Zhicheng, Cao, Zixuan, Pan, Kunqing, Jiang, Ming, Liu, Xia, Wu, Shengxi, Luo, Ceng, Xie, Rou-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582564/
https://www.ncbi.nlm.nih.gov/pubmed/37860084
http://dx.doi.org/10.3389/fnmol.2023.1144614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582564/
https://www.ncbi.nlm.nih.gov/pubmed/37860084
http://dx.doi.org/10.3389/fnmol.2023.1144614

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