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Eotaxin-1/CCL11 promotes cellular senescence in human-derived fibroblasts through pro-oxidant and pro-inflammatory pathways

INTRODUCTION: Eotaxin-1/CCL11 is a pivotal chemokine crucial for eosinophil homing to the lungs of asthmatic patients. Recent studies also suggest that CCL11 is involved in the aging process, as it is upregulated in elderly, and correlated with shorter telomere length in leukocytes from asthmatic ch...

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Detalles Bibliográficos
Autores principales: Lavandoski, Patrícia, Pierdoná, Vinícius, Maurmann, Rafael Moura, Grun, Lucas Kich, Guma, Fatima T. C. R., Barbé-Tuana, Florencia María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582634/
https://www.ncbi.nlm.nih.gov/pubmed/37860000
http://dx.doi.org/10.3389/fimmu.2023.1243537