Rethinking, reducing, and refining the classical oral tyramine challenge test of monoamine oxidase (MAO) inhibitors

The oral tyramine challenge evaluates the safety of novel monoamine oxidase (MAO) inhibitors when taken with tyramine‐containing food or drinks. In its current design, it comprises an extensive series of tyramine escalation steps until a blood pressure threshold is met. Due to the high variation in...

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Detalles Bibliográficos
Autores principales: van Hoogdalem, Ewoud‐Jan, Smith, Karen L., Hartstra, Jan, Constant, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582662/
https://www.ncbi.nlm.nih.gov/pubmed/37596819
http://dx.doi.org/10.1111/cts.13612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582662/
https://www.ncbi.nlm.nih.gov/pubmed/37596819
http://dx.doi.org/10.1111/cts.13612

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