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Effects of triclabendazole and its metabolite exposure on the heart‐rate–corrected QT intervals: A randomized, placebo‐ and positive‐controlled thorough QT study in healthy individuals

Triclabendazole is an effective and well‐tolerated treatment for human fascioliasis. A placebo‐ and positive‐controlled, four‐sequence by four‐period crossover study was conducted in 45 healthy participants to assess the effect of therapeutic (10 mg/kg twice daily [b.i.d.] for 1 day) and supratherap...

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Detalles Bibliográficos
Autores principales: Prince, William T., Venishetty, Vinay Kumar, Lecot, Jean, Shakeri‐Nejad, Kasra, Gray, Cathy, Taylor, Amanda, Iyer, Ganesh R., Zack, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582667/
https://www.ncbi.nlm.nih.gov/pubmed/37688315
http://dx.doi.org/10.1111/cts.13564