Cargando…

Predicting molecular mechanism of silymarin-potentiated diclofenac toxicity: Insight from in silico molecular docking

Silymarin was shown to enhance diclofenac toxicity by inducing the loss of mitochondrial membrane permeability (MMP) in Caco-2 cells, independent of endoplasmic reticulum stress. This study employed in silico molecular docking to further investigate the potential interaction between silymarin and sp...

Descripción completa

Detalles Bibliográficos
Autores principales: Boonyong, Cherdsak, Jianmongkol, Suree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582735/
https://www.ncbi.nlm.nih.gov/pubmed/37859669
http://dx.doi.org/10.1016/j.toxrep.2023.10.001