Hepatic stellate cell-intrinsic role of SOCS1 in controlling hepatic fibrogenic response and the pro-inflammatory macrophage compartment during liver fibrosis

INTRODUCTION: Hepatic stellate cells (HSC) become activated, differentiate to myofibroblasts and produce extracellular fibrillar matrix during liver fibrosis. The hepatic fibrogenic response is orchestrated by reciprocal interactions between HSCs and macrophages and their secreted products. SOCS1 ca...

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Detalles Bibliográficos
Autores principales: Kandhi, Rajani, Yeganeh, Mehdi, Yoshimura, Akihiko, Menendez, Alfredo, Ramanathan, Sheela, Ilangumaran, Subburaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582746/
https://www.ncbi.nlm.nih.gov/pubmed/37860002
http://dx.doi.org/10.3389/fimmu.2023.1259246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582746/
https://www.ncbi.nlm.nih.gov/pubmed/37860002
http://dx.doi.org/10.3389/fimmu.2023.1259246

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