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EBV infection of primary colonic epithelial cells causes inflammation, DDR and autophagy dysregulation, effects that may predispose to IBD and carcinogenesis

EBV is a gammaherpesvirus strongly associated to human cancer. The virus has been shown to play a role also in inflammatory diseases, including IBD, in the context of which colon cancer more frequently arise. In this study, we show for the first time that EBV infects primary colonic epithelial cells...

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Detalles Bibliográficos
Autores principales: Santarelli, Roberta, Evangelista, Lorenzo, Pompili, Chiara, Lo Presti, Salvatore, Rossi, Alberto, Arena, Andrea, Gaeta, Aurelia, Gonnella, Roberta, Gilardini Montani, Maria Saveria, Cirone, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582763/
https://www.ncbi.nlm.nih.gov/pubmed/37797746
http://dx.doi.org/10.1016/j.virusres.2023.199236