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EBV infection of primary colonic epithelial cells causes inflammation, DDR and autophagy dysregulation, effects that may predispose to IBD and carcinogenesis
EBV is a gammaherpesvirus strongly associated to human cancer. The virus has been shown to play a role also in inflammatory diseases, including IBD, in the context of which colon cancer more frequently arise. In this study, we show for the first time that EBV infects primary colonic epithelial cells...
Autores principales: | Santarelli, Roberta, Evangelista, Lorenzo, Pompili, Chiara, Lo Presti, Salvatore, Rossi, Alberto, Arena, Andrea, Gaeta, Aurelia, Gonnella, Roberta, Gilardini Montani, Maria Saveria, Cirone, Mara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582763/ https://www.ncbi.nlm.nih.gov/pubmed/37797746 http://dx.doi.org/10.1016/j.virusres.2023.199236 |
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