Efficacy and safety of ivermectin for the treatment of Plasmodium falciparum infections in asymptomatic male and female Gabonese adults – a pilot randomized, double-blind, placebo-controlled single-centre phase Ib/IIa clinical trial

BACKGROUND: Ivermectin's mosquitocidal effect and in vitro activity against Plasmodium falciparum asexual stages are known. Its in vivo blood-schizonticidal efficacy is unknown. Ivermectin's tolerability and efficacy against P. falciparum infections in Gabonese adults were assessed. METHOD...

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Detalles Bibliográficos
Autores principales: Ekoka Mbassi, Dorothea, Mombo-Ngoma, Ghyslain, Held, Jana, Okwu, Dearie Glory, Ndzebe-Ndoumba, Wilfrid, Kalkman, Laura Charlotte, Ekoka Mbassi, Franck Aurelien, Pessanha de Carvalho, Lais, Inoue, Juliana, Akinosho, Malik Azeez, Dimessa Mbadinga, Lia Betty, Yovo, Emmanuel Koffi, Mordmüller, Benjamin, Kremsner, Peter Gottfried, Adegnika, Ayôla Akim, Ramharter, Michael, Zoleko-Manego, Rella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582777/
https://www.ncbi.nlm.nih.gov/pubmed/37839134
http://dx.doi.org/10.1016/j.ebiom.2023.104814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582777/
https://www.ncbi.nlm.nih.gov/pubmed/37839134
http://dx.doi.org/10.1016/j.ebiom.2023.104814

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