Off-the-shelf CAR–engineered natural killer cells targeting FLT3 enhance killing of acute myeloid leukemia

The majority of patients with acute myeloid leukemia (AML) succumb to the disease or its complications, especially among older patients. Natural killer (NK) cells have been shown to have antileukemic activity in patients with AML; however, to our knowledge, primary NK cells armed with a chimeric ant...

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Detalles Bibliográficos
Autores principales: Mansour, Anthony G., Teng, Kun-Yu, Li, Zhiyao, Zhu, Zheng, Chen, Hanyu, Tian, Lei, Ali, Aliya, Zhang, Jianying, Lu, Ting, Ma, Shoubao, Lin, Chih-Min, Caligiuri, Michael A., Yu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Immunobiology and Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582841/
https://www.ncbi.nlm.nih.gov/pubmed/37379267
http://dx.doi.org/10.1182/bloodadvances.2022007405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582841/
https://www.ncbi.nlm.nih.gov/pubmed/37379267
http://dx.doi.org/10.1182/bloodadvances.2022007405

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