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Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score Catalog

OBJECTIVE: To clarify the performance of polygenic risk scores in population screening, individual risk prediction, and population risk stratification. DESIGN: Secondary analysis of data in the Polygenic Score Catalog. SETTING: Polygenic Score Catalog, April 2022. Secondary analysis of 3915 performa...

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Detalles Bibliográficos
Autores principales: Hingorani, Aroon D, Gratton, Jasmine, Finan, Chris, Schmidt, A Floriaan, Patel, Riyaz, Sofat, Reecha, Kuan, Valerie, Langenberg, Claudia, Hemingway, Harry, Morris, Joan K, Wald, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582890/
https://www.ncbi.nlm.nih.gov/pubmed/37859783
http://dx.doi.org/10.1136/bmjmed-2023-000554