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Reduced Respiratory Syncytial Virus Load, Symptoms, and Infections: A Human Challenge Trial of MVA-BN-RSV Vaccine

BACKGROUND: Respiratory syncytial virus (RSV) causes significant disease burden in older adults. MVA-BN-RSV is a novel poxvirus-vectored vaccine encoding internal and external RSV proteins. METHODS: In a phase 2a randomized double-blind, placebo-controlled trial, healthy participants aged 18 to 50 y...

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Detalles Bibliográficos
Autores principales: Jordan, Elke, Kabir, Golam, Schultz, Stephanie, Silbernagl, Günter, Schmidt, Darja, Jenkins, Victoria A, Weidenthaler, Heinz, Stroukova, Daria, Martin, Barbara K, De Moerlooze, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582911/
https://www.ncbi.nlm.nih.gov/pubmed/37079393
http://dx.doi.org/10.1093/infdis/jiad108