Microglial P2X4 receptors are essential for spinal neurons hyperexcitability and tactile allodynia in male and female neuropathic mice

In neuropathic pain, recent evidence has highlighted a sex-dependent role of the P2X4 receptor in spinal microglia in the development of tactile allodynia following nerve injury. Here, using internalization-defective P2X4mCherryIN knockin mice (P2X4KI), we demonstrate that increased cell surface exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Gilabert, Damien, Duveau, Alexia, Carracedo, Sara, Linck, Nathalie, Langla, Adeline, Muramatsu, Rieko, Koch-Nolte, Friedrich, Rassendren, François, Grutter, Thomas, Fossat, Pascal, Boué-Grabot, Eric, Ulmann, Lauriane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583052/
https://www.ncbi.nlm.nih.gov/pubmed/37860691
http://dx.doi.org/10.1016/j.isci.2023.108110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583052/
https://www.ncbi.nlm.nih.gov/pubmed/37860691
http://dx.doi.org/10.1016/j.isci.2023.108110

Ejemplares similares