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Proteomic profiling of the brain from the wobbler mouse model of amyotrophic lateral sclerosis reveals elevated levels of the astrogliosis marker glial fibrillary acidic protein

The wobbler mouse is a widely used model system of amyotrophic lateral sclerosis and exhibits progressive neurodegeneration and neuroinflammation in association with skeletal muscle wasting. This study has used wobbler brain preparations for the systematic and mass spectrometric determination of pro...

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Detalles Bibliográficos
Autores principales: Murphy, Sandra, Schmitt-John, Thomas, Dowling, Paul, Henry, Michael, Meleady, Paula, Swandulla, Dieter, Ohlendieck, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583141/
https://www.ncbi.nlm.nih.gov/pubmed/37565261
http://dx.doi.org/10.4081/ejtm.2023.11555