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High-dose remifentanil exacerbates myocardial ischemia-reperfusion injury through activation of calcium-sensing receptor-mediated pyroptosis

Background: The aim of this study was to investigate whether calcium-sensing receptor (CaSR) was involved in HRF-mediated exacerbation of MI/R injury through NLRP3 inflammasome activation and pyroptosis. Methods: In vivo, a rat MI/R model was established by ligating the left coronary artery, and sho...

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Detalles Bibliográficos
Autores principales: Zhu, Yejing, Chi, Jinyu, Cai, Shunv, Liu, Siqi, Yuan, Junbo, Xu, Hongliang, Zhou, Huidan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583183/
https://www.ncbi.nlm.nih.gov/pubmed/37859698
http://dx.doi.org/10.7150/ijms.83207