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Population pharmacokinetics of apixaban in a real‐life hospitalized population from the OptimAT study

This study aimed to characterize apixaban pharmacokinetics (PKs) and its variability in a real‐world clinical setting of hospitalized patients using a population PK (PopPK) approach. Model‐based simulations helped to identify factors that affect apixaban exposure and their clinical significance. A c...

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Detalles Bibliográficos
Autores principales: Gaspar, Frédéric, Terrier, Jean, Favre, Samantha, Gosselin, Pauline, Fontana, Pierre, Daali, Youssef, Lenoir, Camille, Samer, Caroline Flora, Rollason, Victoria, Reny, Jean‐Luc, Csajka, Chantal, Guidi, Monia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583248/
https://www.ncbi.nlm.nih.gov/pubmed/37723920
http://dx.doi.org/10.1002/psp4.13032