Engineering siRNA therapeutics: challenges and strategies

Small interfering RNA (siRNA) is a potential method of gene silencing to target specific genes. Although the U.S. Food and Drug Administration (FDA) has approved multiple siRNA-based therapeutics, many biological barriers limit their use for treating diseases. Such limitations include challenges con...

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Detalles Bibliográficos
Autores principales: Ali Zaidi, Syed Saqib, Fatima, Faria, Ali Zaidi, Syed Aqib, Zhou, Dezhong, Deng, Wuquan, Liu, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583313/
https://www.ncbi.nlm.nih.gov/pubmed/37848888
http://dx.doi.org/10.1186/s12951-023-02147-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583313/
https://www.ncbi.nlm.nih.gov/pubmed/37848888
http://dx.doi.org/10.1186/s12951-023-02147-z

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