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Time-sequential fibroblast-to-myofibroblast transition in elastin-variable 3D hydrogel environments by collagen networks

BACKGROUND: Fibrosis plays an important role in both normal physiological and pathological phenomena as fibroblasts differentiate to myofibroblasts. The activation of fibroblasts is determined through interactions with the surrounding extracellular matrix (ECM). However, how this fibroblast-to-myofi...

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Detalles Bibliográficos
Autores principales: Do, Nhuan T., Lee, Sun Young, Lee, Yoon Seo, Shin, ChaeHo, Kim, Daeho, Lee, Tae Geol, Son, Jin Gyeong, Kim, Se-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583321/
https://www.ncbi.nlm.nih.gov/pubmed/37848974
http://dx.doi.org/10.1186/s40824-023-00439-x