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Single-cell characterization of self-renewing primary trophoblast organoids as modeling of EVT differentiation and interactions with decidual natural killer cells

BACKGROUND: Extravillous trophoblast cell (EVT) differentiation and its communication with maternal decidua especially the leading immune cell type natural killer (NK) cell are critical events for placentation. However, appropriate in vitro modelling system and regulatory programs of these two event...

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Detalles Bibliográficos
Autores principales: Zhuang, Bai-Mei, Cao, Dan-Dan, Li, Tian-Xi, Liu, Xiao-Feng, Lyu, Min-Min, Wang, Si-Dong, Cui, Xin-Yuan, Wang, Li, Chen, Xiao-Lin, Lin, Xiao-Li, Lee, Cheuk-Lun, Chiu, Philip C.N., Yeung, William S.B., Yao, Yuan-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583354/
https://www.ncbi.nlm.nih.gov/pubmed/37853336
http://dx.doi.org/10.1186/s12864-023-09690-x