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Niclosamide improves cancer immunotherapy by modulating RNA-binding protein HuR-mediated PD-L1 signaling

BACKGROUND: Immune checkpoint blockade (ICB) represents a revolutionary advance in cancer treatment but remains limited success in triple-negative breast cancer (TNBC). Here we aim to explore the mechanism of RNA-binding protein (RBP) HuR in cancer immune evasion by post-transcriptionally regulating...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Yang, Zhe, Hao, Xinbao, Dandreo, Lauren J., He, Lily, Zhang, Yuxia, Wang, Fen, Wu, Xiaoqing, Xu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583380/
https://www.ncbi.nlm.nih.gov/pubmed/37848943
http://dx.doi.org/10.1186/s13578-023-01137-w