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Neurotrophin-3 promotes peripheral nerve regeneration by maintaining a repair state of Schwann cells after chronic denervation via the TrkC/ERK/c-Jun pathway

BACKGROUND: Maintaining the repair phenotype of denervated Schwann cells in the injured distal nerve is crucial for promoting peripheral nerve regeneration. However, when chronically denervated, the capacity of Schwann cells to support repair and regeneration deteriorates, leading to peripheral nerv...

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Detalles Bibliográficos
Autores principales: Xu, Xiong, Song, Lili, Li, Yueying, Guo, Jin, Huang, Shuo, Du, Shuang, Li, Weizhen, Cao, Rangjuan, Cui, Shusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583391/
https://www.ncbi.nlm.nih.gov/pubmed/37848983
http://dx.doi.org/10.1186/s12967-023-04609-2