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Neurotrophin-3 promotes peripheral nerve regeneration by maintaining a repair state of Schwann cells after chronic denervation via the TrkC/ERK/c-Jun pathway
BACKGROUND: Maintaining the repair phenotype of denervated Schwann cells in the injured distal nerve is crucial for promoting peripheral nerve regeneration. However, when chronically denervated, the capacity of Schwann cells to support repair and regeneration deteriorates, leading to peripheral nerv...
Autores principales: | Xu, Xiong, Song, Lili, Li, Yueying, Guo, Jin, Huang, Shuo, Du, Shuang, Li, Weizhen, Cao, Rangjuan, Cui, Shusen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583391/ https://www.ncbi.nlm.nih.gov/pubmed/37848983 http://dx.doi.org/10.1186/s12967-023-04609-2 |
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