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Endoplasmic reticulum stress related genome-wide Mendelian randomization identifies therapeutic genes for ulcerative colitis and Crohn’s disease

Background: Endoplasmic reticulum stress (ERS) is an important pathophysiological mechanism in ulcerative colitis (UC) and Crohn’s disease (CD). ERS-related genes may be influenced by genetic factors and intestinal inflammation. However, the role of ERS as a trigger or potential etiological factor f...

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Detalles Bibliográficos
Autores principales: Zou, Menglong, Liang, Qiaoli, Zhang, Wei, Zhu, Ying, Xu, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583552/
https://www.ncbi.nlm.nih.gov/pubmed/37860672
http://dx.doi.org/10.3389/fgene.2023.1270085