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A mitochondrial checkpoint to adaptive anticancer immunity

BCL2 robustly preserves mitochondrial integrity, hence inhibiting innate immune signaling and apoptotic cell death in several cell types. Here, we comment on our recent data demonstrating that BCL2 also limits the ability of dendritic cells to elicit adaptive immune responses, lending support to a u...

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Detalles Bibliográficos
Autores principales: Kepp, Oliver, Liu, Peng, Kroemer, Guido, Galluzzi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583618/
https://www.ncbi.nlm.nih.gov/pubmed/37860277
http://dx.doi.org/10.1080/2162402X.2023.2271693