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Pharmacodynamics of ATI-2307 in a rabbit model of cryptococcal meningoencephalitis

Cryptococcal meningoencephalitis (CM) is a devastating fungal disease with high morbidity and mortality. The current regimen that is standard-of-care involves a combination of three different drugs administered for up to one year. There is a critical need for new therapies due to both toxicity and i...

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Detalles Bibliográficos
Autores principales: Giamberardino, Charles D., Tenor, Jennifer L., Toffaletti, Dena L., Palmucci, Julia R., Schell, Wiley, Boua, Jane-Valeriane K., Marius, Choiselle, Stott, Katharine E., Steele, Shelby L., Hope, William, Cilla, Don, Perfect, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583688/
https://www.ncbi.nlm.nih.gov/pubmed/37728934
http://dx.doi.org/10.1128/aac.00818-23