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From random to rational: improving enzyme design through electric fields, second coordination sphere interactions, and conformational dynamics
Enzymes are versatile and efficient biological catalysts that drive numerous cellular processes, motivating the development of enzyme design approaches to tailor catalysts for diverse applications. In this perspective, we investigate the unique properties of natural, evolved, and designed enzymes, r...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583697/ https://www.ncbi.nlm.nih.gov/pubmed/37860658 http://dx.doi.org/10.1039/d3sc02982d |