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Live-Attenuated VEEV Vaccine Delivered by iDNA Using Microneedles Is Immunogenic in Rabbits

Effective and simple delivery of DNA vaccines remains a key to successful clinical applications. Previously, we developed a novel class of DNA vaccines, sometimes called iDNA, which encodes the whole live-attenuated vaccine viruses. Compared to a standard DNA vaccine, an iDNA vaccine required a low...

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Detalles Bibliográficos
Autores principales: Tretyakova, Irina, Tomai, Mark, Vasilakos, John, Pushko, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583749/
https://www.ncbi.nlm.nih.gov/pubmed/37854093
http://dx.doi.org/10.3389/fitd.2022.813671