Post-thaw application of ROCK-inhibitors increases cryopreserved T-cell yield

Emerging cell-based therapies such as CAR-T (Chimeric Antigen Receptor T) cells require cryopreservation to store and deliver intact and viable cells. Conventional cryopreservation formulations use DMSO to mitigate cold-induced damage, but do not address all the biochemical damage mechanisms induced...

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Detalles Bibliográficos
Autores principales: Gonzalez-Martinez, Natalia, Gibson, Matthew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583820/
https://www.ncbi.nlm.nih.gov/pubmed/37859712
http://dx.doi.org/10.1039/d3md00378g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583820/
https://www.ncbi.nlm.nih.gov/pubmed/37859712
http://dx.doi.org/10.1039/d3md00378g

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