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Post-thaw application of ROCK-inhibitors increases cryopreserved T-cell yield
Emerging cell-based therapies such as CAR-T (Chimeric Antigen Receptor T) cells require cryopreservation to store and deliver intact and viable cells. Conventional cryopreservation formulations use DMSO to mitigate cold-induced damage, but do not address all the biochemical damage mechanisms induced...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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RSC
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583820/ https://www.ncbi.nlm.nih.gov/pubmed/37859712 http://dx.doi.org/10.1039/d3md00378g |