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Self-assembly of promoter DNA and RNA Pol II machinery into transcriptionally active biomolecular condensates

Transcription in the nucleus occurs in a concentrated, dense environment, and no reasonable biochemical facsimile of this milieu exists. Such a biochemical environment would be important for further understanding transcriptional regulation. We describe here the formation of dense, transcriptionally...

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Detalles Bibliográficos
Autores principales: Lewis, Brian A., Das, Subhendu Kumar, Jha, Rajiv Kumar, Levens, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584347/
https://www.ncbi.nlm.nih.gov/pubmed/37851801
http://dx.doi.org/10.1126/sciadv.adi4565