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High-content microscopy reveals a morphological signature of bortezomib resistance
Drug resistance is a challenge in anticancer therapy. In many cases, cancers can be resistant to the drug prior to exposure, that is, possess intrinsic drug resistance. However, we lack target-independent methods to anticipate resistance in cancer cell lines or characterize intrinsic drug resistance...
Autores principales: | Kelley, Megan E, Berman, Adi Y, Stirling, David R, Cimini, Beth A, Han, Yu, Singh, Shantanu, Carpenter, Anne E, Kapoor, Tarun M, Way, Gregory P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584373/ https://www.ncbi.nlm.nih.gov/pubmed/37753907 http://dx.doi.org/10.7554/eLife.91362 |
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