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PM2.5 leads to adverse pregnancy outcomes by inducing trophoblast oxidative stress and mitochondrial apoptosis via KLF9/CYP1A1 transcriptional axis

Epidemiological studies have demonstrated that fine particulate matter (PM2.5) is associated with adverse obstetric and postnatal metabolic health outcomes, but the mechanism remains unclear. This study aimed to investigate the toxicological pathways by which PM2.5 damaged placental trophoblasts in...

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Detalles Bibliográficos
Autores principales: Li, Shuxian, Li, Lingbing, Zhang, Changqing, Fu, Huaxuan, Yu, Shuping, Zhou, Meijuan, Guo, Junjun, Fang, Zhenya, Li, Anna, Zhao, Man, Zhang, Meihua, Wang, Xietong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584374/
https://www.ncbi.nlm.nih.gov/pubmed/37737576
http://dx.doi.org/10.7554/eLife.85944