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In silico prediction of deleterious non-synonymous SNPs in STAT3

BACKGROUND: STAT3, a pleiotropic transcription factor, plays a critical role in the pathogenesis of autoimmunity, cancer, and many aspects of the immune system, as well as having a link with inflammatory bowel disease. Changes caused by non-synonymous single nucleotide polymorphisms (nsSNPs) have th...

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Detalles Bibliográficos
Autores principales: Ajith, Athira, Subbiah, Usha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584383/
https://www.ncbi.nlm.nih.gov/pubmed/37860678
http://dx.doi.org/10.2478/abm-2023-0059