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Structural dynamics insights into the M306L, M306V, and D1024N mutations in Mycobacterium tuberculosis inducing resistance to ethambutol

Resistance to anti-tuberculosis drugs, especially ethambutol (EMB), has been widely reported worldwide. EMB resistance is caused by mutations in the embB gene, which encodes the arabinosyl transferase enzyme. This study aimed to detect mutations in the embB gene of Mycobacterium tuberculosis from Pa...

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Detalles Bibliográficos
Autores principales: Maladan, Yustinus, Safari, Dodi, Parikesit, Arli Aditya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584647/
https://www.ncbi.nlm.nih.gov/pubmed/37813628
http://dx.doi.org/10.5808/gi.23019