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Fanconi anemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mouse development
Long interspersed nuclear element 1 (LINE-1) is the only autonomous retrotransposon in humans and new integrations are a major source of genetic variation between individuals. These events can also lead to de novo germline mutations, giving rise to heritable genetic diseases. Recently, a role for DN...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group US
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584689/ https://www.ncbi.nlm.nih.gov/pubmed/37580626 http://dx.doi.org/10.1038/s41594-023-01067-8 |