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Fanconi anemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mouse development

Long interspersed nuclear element 1 (LINE-1) is the only autonomous retrotransposon in humans and new integrations are a major source of genetic variation between individuals. These events can also lead to de novo germline mutations, giving rise to heritable genetic diseases. Recently, a role for DN...

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Detalles Bibliográficos
Autores principales: Bona, Nazareno, Crossan, Gerry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584689/
https://www.ncbi.nlm.nih.gov/pubmed/37580626
http://dx.doi.org/10.1038/s41594-023-01067-8