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Regulation with cell size ensures mitochondrial DNA homeostasis during cell growth

To maintain stable DNA concentrations, proliferating cells need to coordinate DNA replication with cell growth. For nuclear DNA, eukaryotic cells achieve this by coupling DNA replication to cell-cycle progression, ensuring that DNA is doubled exactly once per cell cycle. By contrast, mitochondrial D...

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Detalles Bibliográficos
Autores principales: Seel, Anika, Padovani, Francesco, Mayer, Moritz, Finster, Alissa, Bureik, Daniela, Thoma, Felix, Osman, Christof, Klecker, Till, Schmoller, Kurt M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584693/
https://www.ncbi.nlm.nih.gov/pubmed/37679564
http://dx.doi.org/10.1038/s41594-023-01091-8