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Short-chain fatty acid, butyrate prevents morphine-and paclitaxel-induced nociceptive hypersensitivity

Nociceptive hypersensitivity is a significant side effect with the chronic administration of opioids as well as chemotherapeutics. Both opioid-induced hypersensitivity (OIH) and chemotherapy-induced hypersensitivity (CIH) are characterized by an increased sensitivity to painful stimuli which can sig...

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Detalles Bibliográficos
Autores principales: Jessup, Dawn, Woods, Kareem, Thakker, Sach, Damaj, M. Imad, Akbarali, Hamid I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584825/
https://www.ncbi.nlm.nih.gov/pubmed/37853033
http://dx.doi.org/10.1038/s41598-023-44857-2