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Warburg-associated acidification represses lactic fermentation independently of lactate, contribution from real-time NMR on cell-free systems

Lactate accumulation and acidification in tumours are a cancer hallmark associated with the Warburg effect. Lactic acidosis correlates with cancer malignancy, and the benefit it offers to tumours has been the subject of numerous hypotheses. Strikingly, lactic acidosis enhances cancer cell survival t...

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Detalles Bibliográficos
Autores principales: Daverio, Zoé, Kolkman, Maxime, Perrier, Johan, Brunet, Lexane, Bendridi, Nadia, Sanglar, Corinne, Berger, Marie-Agnès, Panthu, Baptiste, Rautureau, Gilles J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584866/
https://www.ncbi.nlm.nih.gov/pubmed/37853114
http://dx.doi.org/10.1038/s41598-023-44783-3