FSH and ApoE4 contribute to Alzheimer’s disease-like pathogenesis via C/EBPβ/δ-secretase in female mice

Alzheimer’s disease (AD) is the most common dementia. It is known that women with one ApoE4 allele display greater risk and earlier onset of AD compared with men. In mice, we previously showed that follicle–stimulating hormone (FSH), a gonadotropin that rises in post–menopausal females, activates it...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Jing, Kang, Seong Su, Wang, Mengmeng, Wang, Zhihao, Xia, Yiyuan, Liao, Jianming, Liu, Xia, Yu, Shan-Ping, Zhang, Zhaohui, Ryu, Vitaly, Yuen, Tony, Zaidi, Mone, Ye, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584868/
https://www.ncbi.nlm.nih.gov/pubmed/37852961
http://dx.doi.org/10.1038/s41467-023-42282-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584868/
https://www.ncbi.nlm.nih.gov/pubmed/37852961
http://dx.doi.org/10.1038/s41467-023-42282-7

Ejemplares similares