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Chlorogenic acid protects against myocardial ischemia–reperfusion injury in mice by inhibiting Lnc Neat1/NLRP3 inflammasome-mediated pyroptosis

Increasing evidences demonstrate that chlorogenic acid (CGA), a polyphenol with multiple effects such as anti-inflammatory and anti-oxidation, protects against myocardial ischemia–reperfusion injury (MIRI) in vitro and in vivo. But its detailed cardiac protection mechanism is still unclear. The MIRI...

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Detalles Bibliográficos
Autores principales: Chai, Xin, Liang, Zhengwei, Zhang, Junshi, Ding, Jing, Zhang, Qian, Lv, Sha, Deng, Yazhu, Zhang, Rongrui, Lu, Deqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584886/
https://www.ncbi.nlm.nih.gov/pubmed/37853132
http://dx.doi.org/10.1038/s41598-023-45017-2