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Conserved enhancers control notochord expression of vertebrate Brachyury

The cell type-specific expression of key transcription factors is central to development and disease. Brachyury/T/TBXT is a major transcription factor for gastrulation, tailbud patterning, and notochord formation; however, how its expression is controlled in the mammalian notochord has remained elus...

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Detalles Bibliográficos
Autores principales: Kemmler, Cassie L., Smolikova, Jana, Moran, Hannah R., Mannion, Brandon J., Knapp, Dunja, Lim, Fabian, Czarkwiani, Anna, Hermosilla Aguayo, Viviana, Rapp, Vincent, Fitch, Olivia E., Bötschi, Seraina, Selleri, Licia, Farley, Emma, Braasch, Ingo, Yun, Maximina, Visel, Axel, Osterwalder, Marco, Mosimann, Christian, Kozmik, Zbynek, Burger, Alexa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584899/
https://www.ncbi.nlm.nih.gov/pubmed/37852970
http://dx.doi.org/10.1038/s41467-023-42151-3