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Paired yeast one-hybrid assays to detect DNA-binding cooperativity and antagonism across transcription factors

Cooperativity and antagonism between transcription factors (TFs) can drastically modify their binding to regulatory DNA elements. While mapping these relationships between TFs is important for understanding their context-specific functions, existing approaches either rely on DNA binding motif predic...

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Detalles Bibliográficos
Autores principales: Berenson, Anna, Lane, Ryan, Soto-Ugaldi, Luis F., Patel, Mahir, Ciausu, Cosmin, Li, Zhaorong, Chen, Yilin, Shah, Sakshi, Santoso, Clarissa, Liu, Xing, Spirohn, Kerstin, Hao, Tong, Hill, David E., Vidal, Marc, Fuxman Bass, Juan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584920/
https://www.ncbi.nlm.nih.gov/pubmed/37853017
http://dx.doi.org/10.1038/s41467-023-42445-6